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 Home --> Congress Abstracts --> Abstracts

 Congress Abstracts


33rd European Pancreatic Club (EPC) Meeting
Toulouse, France, June 13–16, 2001
Pancreatology 2001;1:129-136



 Guest Editors N.Vaysse, Toulouse
  L.Buscail, Toulouse
C.Susini, Toulouse
L.Pradayrol, Toulouse


     Oral Sessions

     O1  Pancreatic Cancer. Basic and Clinical Aspects
Top

  1. CD44v10 Favors Fibronectin Adhesion and Characterizes Metastatic Pancreatic Cancer Cell Lines
    F. Navaglia, A.L. Stefani, M.G. Piva, P. Fogar, E. Greco, D. Basso, N. Gallo, M. Plebani, S. Pedrazzoli (Italy)
    [Abstract (PDF)]


  2. MUC4 mRNA in Peripheral Blood Mononuclear Cells as a Potential Tumor Marker for Pancreatic Cancer
    G. Faulmann, J. Ringel, R. Brand, N. Moniaux, S.R. Tarantolo, S.S. Joshi, SK. Batra, M. Löhr (USA, Germany)
    [Abstract (PDF)]


  3. Lifestyle Factors and Pancreatic Cancer Risk: A Cohort Study from the Swedish Twin Registry
    B. Isaksson, F. Jonsson, N. Pedersen, J. Larsson, M. Feychting, J. Permert (Sweden)
    [Abstract (PDF)]


  4. Real-Time Quantitative PCR of Telomerase mRNA is Useful for the Differentiation of Benign and Malignant Pancreatic Disorders
    P. Büchler, H. Friess, M.C. Büchler, O.J. Hines, H.G. Beger, J.R. Conejo-Garcia, H.A. Reber, M.W. Büchler (Germany, USA, Switzerland)
    [Abstract (PDF)]


  5. Aberrant Expression and Cell Cycle-Dependent Regulation of ADAM17/TACE in Pancreatic Cancer
    J. Ringel, N. Moniaux, M. Andrianifahanana, G. Faulmann, A. Choudhury, M. Löhr, S.K. Batra (USA, Germany)
    [Abstract (PDF)]


  6. Subcellular Redistribution and Upregulation of the Cell-Adhesion Protein p120ctn in Pancreatic Cancer
    J. Mayerle, H. Friess, M.W. Büchler, J. Schnekenburger, M.M. Lerch (Germany, Switzerland)
    [Abstract (PDF)]



     O2  Gene Therapy
Top

  1. Enzyme-Activation Prodrug/Suicide Gene Therapy of Pancreatic Cancer Using the Bacterial Purine Nucleoside Phosphorylase
    S. Deharvangt, A. Hajri, S. Wack, M. Aprahamian (France)
    [Abstract (PDF)]


  2. Gene Therapy with HSV-TK: A Promising Tool for Pancreatic Cancer Treatment?
    P. Fogar, E. Greco, D. Basso, A. Stefani, C. Pasquali, C. Parolin,G. Palù, S. Pedrazzoli, M. Plebani (Italy)
    [Abstract (PDF)]



     O3  Genetics and Pancreas
Top

  1. The N34S Mutation of PSTI (SPINK1) is Associated with a Familial Pattern of Idiopathic Chronic Pancreatitis but does not Cause the Disease
    J. Threadgold, N. Howes, I. Ellis, I. Gilmore, H. Smart, M. Lombard, W. Greenhalf, J.P. Neoptolemos (UK)
    [Abstract (PDF)]


  2. Trypsin Inhibitor (SPINK1/PST1) Mutations do not Modify the Penetrance or Severity of Hereditary Pancreatitis
    P. Simon, F.U. Weiss, K.P. Zimmer, W. Domaschke, M.M. Lerch (Germany)
    [Abstract (PDF)]


  3. SPINK 1 Mutations are Strongly Associated with Chronic Pancreatitis
    Drenth P.H. Joost, Rene Te Morsche, Jan B.M.J. Jansen (Netherlands)
    [Abstract (PDF)]


  4. VEGF Production in Pancreatic Cancer is Controlled by Hypoxia Inducible Factor (HIF-1)
    P. Büchler, H. Friess, M.C. Büchler, O.J. Hines, H.G. Beger, M.W. Büchler, H.A. Reber (Germany, USA, Switzerland)
    [Abstract (PDF)]



     O4  Acute Pancreatitis: Basic and Clinical Aspects
Top

  1. Intracellular Dynein and Kinesin Kinetics during Acute Experimental Pancreatitis
    I.A. Weber, I. Schnekenburger, I. Buchwalow, M.M. Lerch (Germany)
    [Abstract (PDF)]


  2. Does Mortality Occur Early or Late in Acute Pancreatitis? Survey on 1150 Cases Observed in the Same Center
    G. Uomo, G. Cavallera, G. Manes, M. Visconti, P.G. Rabitti (Italy)
    [Abstract (PDF)]


  3. Cloning of p26, a New p53-dependent Gene Activated in Acinar Cells of the Pancreas with Acute Pancreatitis
    L.A. Azizi Samir, R. Tomasini, M.I. Vaccaro, J.C. Dagorn, N.J. Dusetti, J.L. Iovanna (France)
    [Abstract (PDF)]


  4. Comparative Analysis of Procalcitonin (PCT) and Lipopolysaccharidie Binding Protein (LBP) in the Prediction of Infectious Complications in Acute Pancreatitis
    B. Rau, G. Steinbach, C. Krüger, K. Baumgart, A. Grünert, H.G. Beger (Germany)
    [Abstract (PDF)]



     O5  Pancreatic Development-Transdifferentiation
Top

  1. Overexpression of CCK2/Gastrin Receptors in the Murine Pancreas Results in Proliferation, Transdifferentiation of Acinar Cells and Neoplasia
    P. Clerc, S. Leung-Theung-Long, M. Bouisson, T.C. Wang, G.J. Dockray, N. Vaysse, L. Pradayrol, D. Fourmy, M. Dufresne (France, USA, UK)
    [Abstract (PDF)]


  2. Newly Updated Laguesse’s Theory of Balance: Neogenesis of Pancreatic -Cells Via Acinar Transdifferentiation in Adult Human
    V. Gmyr, J. Kerr-Conte, S. Belaich, T. Bouckenooghe, B. Vandewalle, F. Pattou (France)
    [Abstract (PDF)]


  3. The Exocrine Pancreas-Specific Transcription Factor p48: Role in Experimental Pancreatitis
    M.A. Padilla, X. Molero, A. Skoudy, T. Adell, E. Vaquero, J.A. Gómez-Valero, J.R. Malagelada, F.X. Real (Spain)
    [Abstract (PDF)]



     O6  Pancreatitis. Facts and Prospects
Top

  1. A Specific Alcohol Dehydrogenase 3 Polymorphism Protects against Chronic Pancreatitis
    P.H. Drenth Joost, P.P. Meijer Rowdy, H.M, Peeters Wilbert, B.M.J. Jansen (Netherlands)
    [Abstract (PDF)]


  2. Quality of Life in Patients with Chronic Pancreatitis after Medical Treatment
    S. Kahl, S. Zimmermann, A. Leodolter, B. Glasbrenner, H.U. Schulz, CD. Johnson, P. Malfertheiner (Germany, UK)
    [Abstract (PDF)]


  3. Acute Pancreatitis: When and Why do Patients Die? is Death Predictable?
    U. Haac, T. Blum, P. Maisonneuve, A.B. Lowenfels, P.G. Lankisch (Germany, Italy, USA)
    [Abstract (PDF)]


  4. Gene Expression Profile Analysis during Acute Pancreatitis Reveales Increased Expression Activity and Previously Unreported Genes
    P. Michel, S. Benz, M. Löbler, H.J. Thiesen, D. Koczan, U.T. Hopt (Germany)
    [Abstract (PDF)]



     O7  Acute Pancreatitis. Stress and Inflammation
Top

  1. Pancreatic Changes in TNBS-Induced Colitis in Mice
    M. Barthet, L. Dubucquoy, S. Garcia, P. Desreumaux, J. Iovanna, J.F. Colombel, J.C. Dagorn (France)
    [Abstract (PDF)]


  2. Preprotachykinin-A Gene Deletion in Mice Affords Protection against Acute Pancreatitis-Associated Lung Injury
    M. Bhatia, J. Slavin, Y.Q. Cao, A.I. Basbaum, J.P. Neoptolemos (UK, USA)
    [Abstract (PDF)]



     O8  Pancreatic Cancer. Further Basic Aspects
Top

  1. Activation of the Cholecystokinin-B/Gastrin Receptor (RCCKB) Induces Reorganization of Actin and Reduction of Cell Adhesion in Epithelial Cells
    C. Bierkamp, A. Kowalski-Chauvel, S. Dehez, D. Fourmy, L. Pradayrol, C. Seva (France)
    [Abstract (PDF)]


  2. Differential Activation of P42ERK2 and P125FAK by Cholecystokinin and Bombesin in Secretion and Proliferation in AR42J Cells
    K. Kiehne, K.H. Herzig, U.R. Fölsch (Germany)
    [Abstract (PDF)]


  3. Differential Gene Expression Underlying the Inhibition of Cell Proliferation by Cholecystokinin-A Receptors in Human Pancreatic Cancer Cells
    G. Rácz, C. Wenger, B. Burghardt, K. Barabás, C.D. Logsdon, T.M. Gress, G. Varga (Hungary, Germany, USA)
    [Abstract (PDF)]


  4. Ectopic Cytoplasmic Expression of -Catenin Correlates with Cyclin D1 Overexpression in Pancreatic Cancer
    M. Ramadani, Q. Qiao, F. Gansauge, S. Gansauge, G. Leder, H.G. Beger (Germany)
    [Abstract (PDF)]



     O9  Pancreatic Surgery
Top

  1. Nasogastric Feeding is a Safe and Practical Alternative in Severe Acute Pancreatitis. A Randomised Controlled Trial
    F.C. Eatock, P.S. Chong, N. Menezes, C.J. McKay, C.W. Imrie, C.R. Carter (Scotland)
    [Abstract (PDF)]


  2. Differences in Results of Pancreatic Resections in Finnish Hospitals
    M. Parviainen, J. Sand, I. Nordback (Finland)
    [Abstract (PDF)]


  3. Microarray Analysis of Gene Expression in Pancreatic Ischemia/Reperfusion Injury
    S. Benz, M. Löbler, R. Obermaier, B. Kortmann, D. Kocian, H.J. Thiesen, F. Pfeffer (Germany)
    [Abstract (PDF)]



     O10  Endoscopy and Pancreatic Imaging
Top

  1. Evaluation of Pancreatic Exocrine Function by Means of Secretin-Enhanced MR Cholangio-Pancreatography (S-MRCP)
    L. Czakó, J. Endes, T. Takacs, J. Lonovics (Hungary)
    [Abstract (PDF)]


  2. Role of 18-FDG-PET in Preoperative Evaluation of Patients with Cystic Lesions of the Pancreas
    C. Sperti, C. Pasquali, G. Ferlin, G. Liessi, F. Chierichetti, S. Pedrazzoli (Italy)
    [Abstract (PDF)]


  3. Prospective Evaluation of New Ultra-fast MRT versus Endosonography in Pancreatic Lesions Suspicious of Cancer or Chronic Pancreatitis
    B. Junge, S. Ruehm, J. Zeeh, W. Niebel, K.J. Oldhafer, G. Gerken, J.F. Debatin, M. Rünzi (Germany)
    [Abstract (PDF)]


  4. Dorsal Duct Stenting and Endoscopic Sphincterotomy of the Minor Papilla in Pancreas Divisum
    L. Heyries, M. Barthet, C. Delvasto, C. Zamora, J.P. Bernard, J. Sahel (France)
    [Abstract (PDF)]


  5. Gabexate or Somatostatin Administration before ERCP in Patients at Risk for Post-Intervention Pancreatitis: A Placebo-Controlled, Randomized, Clinical Trial
    A. Andriulli, R. Clemente, L. Solmi, R. Terruzzi, R. Suriani, A. Sigillito, G. Leandro, G. De Maio, F. Perri (Rotondo)
    [Abstract (PDF)]



     Poster Sessions

     P1  Cell Biology, Physiology and Pharmacology
Top

  1. Characterization and Traffic of Carbonic Anhydrase IV in Human Pancreatic Duct Cells (Capan-1 Line)
    C. Salvador, L. Alvarez, M. Fanjul, N. Carter, E. Hollande (France, UK)
    [Abstract (PDF)]


  2. Effects of Dibutyltin Dichloride (DBTC) on Rat Pancreatic Acinar Cells
    J. Merkord, H. Weber, L. Jonas (Germany)
    [Abstract (PDF)]


  3. Mechanisms of HCO3– Secretion in Murine Pancreatic Ducts
    M.P. Fernández-Salazar, J.I. San Román, P. Pascua, J.J. Calvo, R.M. Case, MC. Steward (UK)
    [Abstract (PDF)]


  4. N -Methyl Histamine Inhibits Pancreatic Secretion in Rats
    J. Bilski, A. Szlachcic, J. Jaworek, M. Cieszkowski, A. Dembinski, Z. Warzecha, K. Nawrot, S.J. Konturek (Poland)
    [Abstract (PDF)]


  5. Effect of Secretin, VIP, PACAP-38 and CCK on Pancreatic Ductal Bicarbonate Secretion in Guinea-pig
    G. Szalmay, G. Varga, R.M. Case, M.C. Stewart (Hungary, UK)
    [Abstract (PDF)]


  6. Substance-P Inhibits Pancreatic Ductal Bicarbonate Secretion in Guinea Pig
    P. Hegyi, M.A. Gray, B.E. Argent (UK)
    [Abstract (PDF)]


  7. Effect of Pharmacological Blockade of Muscarinic Receptors on Food-Stimulated Secretion of Pancreatic Juice of Conscious Weaned Pigs
    J. Wolin ´ski, W. Korczyn´ski, M. Babelewka, R. Zabielski (Poland)
    [Abstract (PDF)]


  8. ATP And ATPase Activity in Human and Rodent Pancreatic Juice
    K. Kordás, A. Kittel, B. Sperlágh, T. Tihanyi, G. Varga (Hungary)
    [Abstract (PDF)]


  9. A New High Throughput Assay to Measure Pancreatic Enzyme Activities in Biological Samples
    R. Schwab, É. Németh, B.B. Németh, M. Tejeda, T. Gyökeres, Á. Pap (Hungary)
    [Abstract (PDF)]


  10. Effect of Exogenous Leptin on the Secretion of Pancreatic Juice in Anaesthetized Rat
    R. Zabielski, J. Wolin ´ski, S. Kato (Poland, Japan)
    [Abstract (PDF)]


  11. Leptin Stimulates Exocrine Pancreatic Secretions Through a CCK-1 Receptor Dependent Pathway and Vagal Afferences
    S. Guilmeau, C. Nagain-Domaine, M. Buyse, H. Goiot, A. Bado, C. Rozé (France)
    [Abstract (PDF)]


  12. Kidney Bean Lectin Induces Rapid Development of the Pancreas in Suckling Piglets
    M. Biernat, K. Radberg, A. Linderoth, R. Zabielski, B. Weström, S.G. Pierzynowski (Poland, Sweden)
    [Abstract (PDF)]


  13. Islet Amyloid Polypeptide (IAPP) Controls Food Intake Through Actions on the Brain
    M. Olsson, J. Permert, R. Reidelberger, J. Larsson, U. Arnelo (Sweden)
    [Abstract (PDF)]


  14. Specific Binding of Proinsulin C-peptide to Intact Living Cells and Detergent-Solubilized Cell Extracts
    A. Pramanik, M. Henriksson, J. Shafqat, Z. Zhong, M. Tally, K. Ekberg, J. Wahren, R. Rigler, J. Johansson, H. Jörnvall (Sweden)
    [Abstract (PDF)]


  15. Functions of CCK-2 Receptor in -Pancreatic Cells
    S. Leung-Theung-Long, S. Marchal, J. Philippe, C. Escrieut, P. Clerc, L. Pradayrol, D. Fourmy, M. Dufreshne (France)
    [Abstract (PDF)]


  16. Expression of Inhibins and Activins in Pancreatic Islets and Pancreatic Endocrine Tumors
    S. La Rosa, S. Uccella, A. Genasetti, F. Sessa, C. Capella (Italy)
    [Abstract (PDF)]


  17. Cholecystokinin Release by the Novel Peptide Apelin through Voltage-gated Calcium Channels
    K. Kiehne, M. Höpfner, H. Scherübl, J. Walkowiak, K. Tatemoto, U.R. Fölsch, K.H. Herzig (Germany, Japan)
    [Abstract (PDF)]


  18. JMV-180 Differs from CCK by a Distinct Binding Site Which Allows a Differential Activation of the CCK-1 Receptor
    E. Archer, C. Escrieut, B. Maigret, J. Martinez, L. Moroder, L. Pradayrol, D. Fourmy (France)
    [Abstract (PDF)]



     P2  Cancer. Basic Aspects
Top

  1. Tumor Hypoxia Predicts Metastatic Tumor Growth In Vivo and Regulates the Angiogenic Cytokine VEGF
    P. Büchler, H. Friess, M.C. Büchler, O.J. Hines, H.G. Beger, M.W. Büchler, H.A. Reber (Germany, USA, Switzerland)
    [Abstract (PDF)]


  2. Autocrine and Paracrine Regulation of Angiogenesis in Human Pancreatic Cancer: A Preliminary study
    I. Esposito, D. Campani, M. Menicagli, U. Boggi, E. Parrini, F. Mosca, G. Bevilacqua (Italy)
    [Abstract (PDF)]


  3. The Presence and Differential Degradation of the Angiogenesis Inhibitor Endostatin in Pancreatic Tissue and SUIT–2 Cell Lines
    R.D. Brammer, S.R. Bramhall, M.C. Eggo (UK)
    [Abstract (PDF)]


  4. Nerve Growth Factor Influences Differently the Growth of Pancreatic Cancer Cells
    Z.W. Zhu, A.A. Tempia-Caliera, H. Friess, L. Wang, T. Bogardus, M. Korc, J. Kleef, M.W. Büchler (USA)
    [Abstract (PDF)]


  5. Selective Activation of PKC-Independent P42–P44 Mitogen Activating Protein Kinases Pathway by a Constitutive Cholecystokinin 2 Receptor Mutant
    C. Galés, C. Berge, L. Moroder, L. Pradayrol, D. Fourmy, S. Silvente-Poirot (France, Germany)
    [Abstract (PDF)]


  6. Role of the Atypical Isoform of Protein Kinase C in Pancreatic Adenocarcinoma Cell Motility
    C. Laudanna, A. Bonora, C. Sorio, C. Bassi, C. Tecchio, P. Pederzoli, A. Scarpa (Italy)
    [Abstract (PDF)]


  7. Galectins are Dysregulated in Human Pancreatic Cancer
    A. Tempia-Caliera, H. Friess, P.O. Berberat, L. Wang, Z.W. Zhu, T. Bley, L. Frigeri, A. Zimmermann, M.W. Büchler (Switzerland, USA)
    [Abstract (PDF)]


  8. Inhibitory Effect of the Lectin WGA on the Proliferation of Rat Pancreatic Tumour Line AR42J
    L. Jonas, U. Mikkat, B. Nebe, E. Albrecht, H. Nizze (Germany)
    [Abstract (PDF)]


  9. Activation of Somatostatin sst2 Receptors Inhibits Cell Growth Induced by the Overexpressed 24 kDa FGF-2 Isoform in Pancreatic Cancer Cells
    M. Hortala, C. Bertrand, C. Susini, L. Pradayrol, F. Clemente, A. Estival (France)
    [Abstract (PDF)]


  10. NSC-631570 Induces Apoptosis in Pancreatic Cancer Cells – An Old Highly Potent Drug Against Pancreatic Cancer
    M. Ramadani, S. Gansauge, B. Muehling, H.G. Beger, F. Gansauge (Germany)
    [Abstract (PDF)]


  11. Caspase-1-Inhibition Induces Cell Death in Pancreatic Carcinoma Cell Lines
    S. Schlosser, F. Gansauge, M. Ramadani, H.G. Beger, S. Gansauge (Germany)
    [Abstract (PDF)]


  12. Neuronal Nitric Oxide Synthase (nNOS): A Substrate for SHP-1 Involved in SST2 Somatostatin Receptor Signal
    F. Lopez, G. Ferjoux, P. Cordelier, N. Saint-Laurent, J.P. Estève, N. Vaysse, L. Buscail, C. Susini (France)
    [Abstract (PDF)]


  13. Comparison of Protein Profiles from Normal and Malignant Pancreatic Ductal Cells
    A.R. Shekouh, W. Prime, J. Hamlett, B. Terris, T. Crnogorac-Jurcevic, N. Lemoine, S. Pennington, C.S. Herrington, J.P. Neoptolemos, E. Costello (UK)
    [Abstract (PDF)]


  14. Real-Time K-Ras Mutational Analysis Diagnosis of Early Pancreatic Duct Adenocarcinoma
    T. Wong, N. Howes, M.G. Lombard, H.L. Smart, I. Gilmore, R. Sutton, F. Campbell, Y. Kang, I. Ellis, W. Greenhalf, J.P. Neoptolemos (UK)
    [Abstract (PDF)]


  15. Screening Pancreatic Juice for p53 Mutations Using a Yeast Functional Assay
    J. Threadgold, N. Howes, I. Ellis, I. Gilmore, H. Smart, M. Lombard, W. Greenhalf, J.P. Neoptolemos (UK)
    [Abstract (PDF)]


  16. Constitutive Co-expression of CD137 (4-1BB) and CD137 Ligand as Members of the Tumor Necrosis Factor Receptor and Ligand Families, in Pancreatic Cancer Cells
    J. Ringel, G. Faulmann, N. Moniaux, J. Ringel, S. Batra, M. Löhr (Germany, USA)
    [Abstract (PDF)]


  17. Cytotoxic Drugs Combined with Adenoviral-Mediated Introduction of Tumour Suppressor Genes Act Synergistically to Decrease Pancreatic Cancer Cell Viability
    C.M. Halloran, P. Ghaneh, J.P. Neoptolemos, E. Costello (UK)
    [Abstract (PDF)]


  18. The Immune Antitumor Effect of E. coli Cystosine Deaminase Suicide Gene is Enhanced by Adjunction of IL12 DNA In Vivo-Electroporation
    A. Hajri, S. Wack, C. Nicolau, M. Aprahamian (France)
    [Abstract (PDF)]


  19. Nuclear Factor Kappa B (NF-B) and Pancreatic Cancer Treatment
    M.I. Hussain, Y. Kyung Kang, J.P. Neoptolemos, E. Costello (UK)
    [Abstract (PDF)]


  20. Lysozyme Expression in Pancreatic Cancer – An Independent Prognostic Factor
    M. Ramadani, S. Gansauge, Z. Stankovic, F. Gansauge, H.G. Beger (Germany)
    [Abstract (PDF)]


  21. Metastasis-Associated Genes are Differentially Expressed in Pancreatic and Papilla of Vater Cancer and Correlate with Prognosis
    H. Friess, X.Z, Guo, A.A. Tempia-Caliera, A. Zimmermann, M.W. Büchler (Switzerland)
    [Abstract (PDF)]


  22. Cytostatic Sensitivity of Multidrug-Resistant & Sensitive Human Gastrointestinal Cancer Cell Lines
    K. Diófalvi, R.E. Schwab, T. Micsik, M. Tejeda, T. Gyökeres, A. Jassó, J. Kamuti, K. Oreskovinch, B. Sarkadi, Á. Pap (Hungary)
    [Abstract (PDF)]


  23. Obstructive Jaundice Results in Increased Liver Expression of Uncoupling Protein 2 and Intact Skeletal Muscle Glucose Metabolism in the Rat
    B. Isaksson, C. Rippe, R. Simonoska, J.E. Holm, R. Segersvärd, J. Larsson, C. Erlanson-Albertsson, J. Permert (Sweden)
    [Abstract (PDF)]


  24. A 2030 D Peptide as the Putative Pancreatic Cancer-Associated Diabetogenic Factor
    S. Mazza, D. Basso, A. Valerio, R. Seraglia, E. Greco, C.F. Zambon, N. Gallo, P. Fogar, S. Pedrazzoli, A. Tiengo, M. Plebani (Italy)
    [Abstract (PDF)]



     P3  Acute Pancreatitis. Clinical Aspects
Top

  1. Acute Pancreatitis in Children, a Multicenter Study
    R. Pezzilli, A.M. Morselli-Labate, E. Castellano, C. Barbera, S. Corrao, L. Di Prima, V. Lucidi, A. Carroccio (Italy)
    [Abstract (PDF)]


  2. Acute Pancreatitis in Italy: A Multicenter Study on 1005 Patients
    G. Cavallini, G. Uomo, R. Pezzilli, L. Frulloni, De Rai, V. Di Carlo, G. Costamagna, P. Pederzoli (Italy)
    [Abstract (PDF)]


  3. Mortality Rate from Acute Pancreatitis in Lviv (Ukraine), 1990–2000
    A. Perejaslov, S. Chooklin (Ukraine)
    [Abstract (PDF)]


  4. Simply Ask the Patient When Symptoms Started to Predict Severity of Acute Pancreatitis
    H.-M. Werner, T. Blum, P. Maisonneuve, A.B. Lowenfels, P.G. Lankisch (Italy, USA)
    [Abstract (PDF)]


  5. Usefulness of Carbophydrate-Deficient Transferrin and Trypsin Activity in the Diagnosis of Acute Alcoholic Pancreatitis
    J.R. Aparicio, J.A. Viedma, L. Aparisi, S. Navarro, J. Martínez, M. Pérez-Mateo (Spain)
    [Abstract (PDF)]


  6. Level of Polyunsaturated Fatty Acids in Free Fatty Acid Fraction of Blood Serum in Patients with Severe Acute Pancreatitis
    J. Panek, D. Karcz, K. Sztefko (Poland)
    [Abstract (PDF)]


  7. Lipopolysaccharide Binding Protein (LBP) in Acute Pancreatitis: Clinical Value of an Alterntive Acute-Phase Parameter for Automated Analysis
    B. Rau, G. Steinbach, K. Baumgart, C. Krüger, A. Grünert, H.G. Beger (Germany)
    [Abstract (PDF)]


  8. Urinary Trypsinogen Activation Peptide (uTAP) for Prediction of Severity in Patients with Acute Pancreatitis within 24h of Onset of Symptoms
    C.D. Johnson, M. Lempinen, C. McKay, J. Dowle, P. Puolakkainen, E. Kemppainen, C.W. Imrie (UK, Finland)
    [Abstract (PDF)]


  9. Clinical Relevance of Elevated Serum Cortisol Levels in Acute Pancreatitis
    C.M. Krüger, B. Rau, K. Baumgart, G. Steinbach, H.G. Beger (Germany)
    [Abstract (PDF)]


  10. Acute Pancreatitis: Which Patient is at Risk of Having a Fluid Collection on Admission or a Pseudocyst at Discharge from Hospital?
    P.G. Lankisch, H. Luebbers, T. Blum, R. Mahlke, P. Maissonneuve, A.B. Lowenfels (Italy, USA)
    [Abstract (PDF)]


  11. Multi-organ Failure, Inflammatory and Nutritional Response Markers in Acute Pancreatitis
    M.V. De la Torre-Prados, M.A. Herce-Muñoz, M. Morell-Ocaña, F. Rías-Diaz, A. García-Alcántara (Spain)
    [Abstract (PDF)]


  12. Failure of the Atlanta Classification to Identify Patients with Poor Prognosis in Necrotizing Pancreatitis
    R. Isenmann, B. Rau, H.G. Beger (Germany)
    [Abstract (PDF)]


  13. Prognostic Value of Endotoxemia in Acute Pancreatitis
    J. Martínez, J.M. Palazón, C. Muñoz, J. Sánchez-Payá, R. Laveda, M. López, M. Pérez-Mateo (Spain)
    [Abstract (PDF)]


  14. Effect of N-Acetyl Cysteine on Acute Pancreatitis Induced by Pancreatic Duct Obstruction in Rats
    S. Sevillano, A.M. De la Mano, I. De Dios, A. Uruñuela, L. Ramudo, M.A. Manso (Spain)
    [Abstract (PDF)]


  15. CCK Blockade does not Reduce the Severity of Acute Pancreatitis Induced by Pancreatic Duct Obstruction in Rats
    A. Uruñuela, M.A. Manso, S. Sevillano, A.M. de la Mano, L. Ramudo, I. de Dios (Spain)
    [Abstract (PDF)]


  16. Minimally Invasive Pancreatic Necrosectomy: Effect on Outcome and Comparision with Open Necrosectomy
    P. Ghaneh, P. Rowlands, R. Sutton, M.R. Hartley, C. Garvey, M. Hughes, J.P. Neoptolemos, J. Slavin (UK)
    [Abstract (PDF)]


  17. Intraoperatively Introduced Guidewire Reduces the Risk for Pancreatitis During ERCP?
    U.L. Enochsson, B. Lindberg, J. Permert, U. Arnelo (Sweden)
    [Abstract (PDF)]


  18. A Minimally Invasive Technique Reduces the Need for Post-Operative Intensive Care in the Surgical Management of Infected Pancreatic Necrosis
    C.W. Imrie, P.S. Chong, C.J. McKay, C.R. Carter (Scotland)
    [Abstract (PDF)]


  19. Complex Endoscopic Treatment of Pancreatic Fistulas
    Á. Pap, M. Gyökeres, T. Burai, L. Tihanyi, L. Flautner (Hungary)
    [Abstract (PDF)]


  20. Glucose Impaired Tolerance and Overt Diabetes Incidence in Patients Recovered from Acute Pancreatitis (AP)
    E. Malecka-Panas, A. Gasiorowaska, A. Kropiwnicka, J. Drzewoski (Poland)
    [Abstract (PDF)]



     P4  Acute Pancreatitis. Basic Aspects
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  1. Comparision of Two Models of Acute Necrotising Pancreatitis Induced by Excess Lysine and Arginine in Rats
    N. Lasztity, R. Schwab, A. Gelley, M. Antal, Á. Pap (Hungary)
    [Abstract (PDF)]


  2. Pancreatic Ischemia/Reperfusion: Characterisation of Microcirculatory Disorders in Dependence to the Ischemic Period
    R. Obermaier, S. Benz, E. Von Dobschütz, O. Drognitz, L. Jonas, U.T. Hopt (Germany)
    [Abstract (PDF)]


  3. Specific Trypsinogen Degradation by Cathepsin L
    W. Halangk, T. Reinheckel, T. Kähne, B. Schmidt, M.M. Lerch (Germany)
    [Abstract (PDF)]


  4. Role of Free Fatty Acids in Necrotizing Pancreatitis: An In Vivo Experimental Study
    F. Paye, O. Presset, J. Chariot, G. Molas, C. Rozé (France)
    [Abstract (PDF)]


  5. Acute Experimental Pancreatitis is Associated with an Increased Expression of Uncoupling Protein 2 in the Pancreas
    R. Segersvärd, C. Rippe, B. Isaksson, J. Permert, C. Erlanson-Albertson (Sweden)
    [Abstract (PDF)]


  6. The Pancreatitis-Associated Protein Induces Lung Inflammation through Activation on TNF Expression by Hepatocytes
    E. Folch, J.L. Iovanna, J.C. Dagorn, N. Prats, A. Garcia-Montero, M.I. Vaccaro, J. Roselló-Catafau, E. Gelpí, D. Closa (Spain, France, Argentina)
    [Abstract (PDF)]


  7. Intestinal pH and Staphylococcus Contamination of Pancreas, Liver and Spleen during Experimental Acute Pancreatitis in Mice
    R. Delcenserie, A. Menudier, T. Yzet, H. Sevestre, J.L. Dupas (France)
    [Abstract (PDF)]


  8. Soluble Receptors Released during Acute Pancreatitis Interferes the Detection on TNF
    E. Folch, A. Serrano, L. Sabater, E. Gelpí, J. Roselló-Catafau, D. Closa (Spain)
    [Abstract (PDF)]


  9. Intracellular Trypsinogen Activation is not Involved in Acinar Cell Necrosis but may Have a Protective Role
    M. Ruthenbürger, B. Krüger, W. Halangk, M.M. Lerch (Germany)
    [Abstract (PDF)]


  10. Inhibition of the Angiotensin Converting Enzyme and Blockade of the Angiotensin II Receptors Protects Pancreatic Tissue in Caerulein Induced Pancreatitis
    W.W. Pawlik, R. Sendur, J. Biernat, R. Obuchowicz, A. Dembin´ski, Z. Warzecha, J. Jaworek (Poland)
    [Abstract (PDF)]


  11. Treatment with Met-RANTES Protects Mice Against Acute Pancreatitis-Associated Lung Injury
    M. Bhatia, A.E.I. Proudfoot, T.N.C. Wells, S.E. Christmas, J.P. Neoptolemos, J. Slavin (UK, Switzerland)
    [Abstract (PDF)]


  12. Hepatocyte Growth Factor Increases Interleukin 10 and Reduces Pancreatic Damage in Experimental Pancreatitis
    A. Dembin´ski, Z. Warzecha, P. Ceranowicz, J. Jaworek, P.C. Konturek, J. Bilski, W. Pawlik, R. Sendur, S.J. Konturek (Poland)
    [Abstract (PDF)]


  13. Reduction of Pancreatic Ischemia/Reperfusion Injury by Inhibition of Neuronal Nitric Oxide Synthase (nNOS)
    R. Obermaier, S. Benz, O. Drognitz, U.T. Hopt (Germany)
    [Abstract (PDF)]


  14. Melatonin and its Precursor; L-Tryptofan Reduces Ischemia–Reperfusion Injury and Lipid Peroxidation in the Rat Pancreas
    J. Jaworek, J. Bonior, A. Leja, R. Tomaszewka, W. Pawlik, R. Sendur, M. Kot, A. Dembinski, Z. Warzecha, J. Stachura, S.J. Konturek (Poland)
    [Abstract (PDF)]


  15. Endegenous Melatonin and its Receptor in the Protection of the Pancreas against Caerulein Induced Pancreatitis
    J. Jaworek, J. Bonior, A. Leja, K. Nawrot, M. Kot, J. Bilski, R. Sendur, W.W. Pawlik, A. Dembin´ski, S.J. Konturek (Poland)
    [Abstract (PDF)]


  16. Capsaicin or CGRP Attenuates Pancreatic Damage in Ischemia–Reperfusion (I/R) Induced Pancreatitis
    A. Dembin´ski, Z. Warzecha, P. Ceranowicz, R. Sendur, W. Pawlik, J. Jaworek, S.J. Konturek (Poland)
    [Abstract (PDF)]


  17. SNAP and VIP Prevents Hypotension in Taurocholate-Induced Acute Pancreatitis
    E. Hernández-Barbáchano, J.I. San Román, M.A. López, J.J. Calvo (Spain)
    [Abstract (PDF)]


  18. Effects of FK 506 on Pancreatic Acinar Cell Damage in Taurocholate Induced Acute Experimental Pancreatitis
    B. Rau, C. Krüger, A.S. Paszkowski, S. Lillich, J.M. Mayer, P. Möller, H.G. Beger (Germany)
    [Abstract (PDF)]


  19. An Interleukin-8 Microsatellite Allele is Associated with Improved Outcome in Predicted Severe Acute Pancreatitis
    P.S. Chong, J. Eskdale, G. Gallagher, C.W. Imrie, C.R. Carter, C.J. McKay (Scotland)
    [Abstract (PDF)]



     P5  Cancer. Clinical Aspects
Top

  1. New Tumormarkers p53-Antibody, M2PK and Tissue Factor for Detecting Pancreatic Carninoma
    F. Hummel, H. Hinner, C. Zingler, S. Liebe, M. Löhr (Germany)
    [Abstract (PDF)]


  2. The Sensitivity of the Intraductal Cytology and Biopsy in Pancreatobiliary Malignancies
    E. Schäfer, T. Gyökeres, A. Gelley, M. Burai, G. Elek, B. Tihanyi, Á. Pap (Hungary)
    [Abstract (PDF)]


  3. Diagnostic Value of Plasma Cromogranin A in Endocrine Tumors of the Pancreas
    M. Migliori, S. Lalli, D. Campana, R. Corinaldesi, L. Gullo, P. Tomassetti (Italy)
    [Abstract (PDF)]


  4. Ultrasound Guided Percutaneous Pancreatic Biopsy: Further Experience
    C.E. McNaught, S. Morris, I. Renwick, D.R. Morgan, J. MacFie, C.J. Mitchell (England)
    [Abstract (PDF)]


  5. Mass-Forming Pancreatitis (MFP) and Pancreatic Cancer (PC): A Diagnostic Problem
    L. Frulloni, C. Liani, P. Bovo, B. Vaona, B. Calore, A. Cantone, R. Turrini, G. Gasparini, S. Carrara, G. Cavallini (Italy)
    [Abstract (PDF)]


  6. Does Medial Pancreatectomy Carry Drawbacks?
    A. Sauvanet, C. Partensky, B. Sastre, J.F. Gigot, P.L. Fagniez, J.P. Arnaud, B. Millat, S. Berdah, B. Dousset, D. Jaeck, P. Le Treut C. Letoublon (France)
    [Abstract (PDF)]


  7. Pancreatic Enucleation: Limits of an Attractive Procedure
    A. Sauvanet, B. Dousset, C. Proye, D. Jaeck, J.P. Arnaud, J.F. Gigot, C. Leborgne, C. Partensky, C. Letoublon, P.L. Fagniez, S. Berdah, P. Le Treut (France)
    [Abstract (PDF)]


  8. Pancreatico-Duoenectomy in the Elderly
    D. Roy, J.A. Pain (UK)
    [Abstract (PDF)]


  9. The Role of Pancreatic Resection for Metastatic Tumors to the Pancreas
    C. Sperti, C. Pasquali, L. Pinciroli, A. Ferronato, S. Pedrazzoli (Italy)
    [Abstract (PDF)]


  10. The Contribution to Survival After Palliative Surgery for Pancreatic Carcinoma
    M. Ryska, R. Strnad, F. Belina, M. Zavoral, J. Špicák (Czech Republic)
    [Abstract (PDF)]


  11. Radiation Therapy (RT), Concurrent Gemcitabine (GEM) and Infusional 5-Fluorouracil (5FU) in Patients with Localized Unresectable Pancreatic Adenocarcinoma
    G. Boz, A. De Paoli, R. Innocente, C. Rossi, G.C. Tosolini, P. Pederzoli, R. Talamini, M.G. Trovò (Italy)
    [Abstract (PDF)]


  12. Targeted Dietary Intervention After Pancreatic Resection for Malignancy. Effects on Bowel Function and Quality of Life
    T. Armstrong, E. Walters, S. Varshney, C.D. Johnson (UK)
    [Abstract (PDF)]


  13. Prognostic Factors in the Operative and Palliative Treatment of Pancreatic Cancer
    R. Talar-Wojnarowska, A. Gasiorowska, J. Strzelczyk, A. Janiak, E. Malecka-Panas (Poland)
    [Abstract (PDF)]


  14. Development of the ESPAC Questionnaire for Assessment of Pancreatic Specific Quality of Life
    D.D. Stocken, J.A. Dunn, J. Almond, J.P. Neoptolemos (UK)
    [Abstract (PDF)]



     P6  Chronic Pancreatitis. Basic Aspects
Top

  1. Mutation of PSTI and CFTR Genes in Patients with Pancreatitis
    P. Salacone, C. Bancone, M. Gallo, M. Bardessono, G. Gerbino Promis, P. Salmin, E. Gaia, C. Arduino (Italia)
    [Abstract (PDF)]


  2. Genes Encoding Proteins of the Extracellular Matrix and of the Immune System are Overexpressed in Chronic Calcifying Pancreatitis
    M. Löbler, U. Adam, H. Prall, H. Nizze, D. Koczan, H.-J. Thiesen. U.T. Hopt (Germany)
    [Abstract (PDF)]


  3. A High Activity Polymorphism in the Promoter Region of Alcohol Inducible Enzyme Cytochrome P450 2E1 in Alcoholism and End Organ Disease
    M.T. Cartmell, H.-U. Schulz, D.A. O’Reilly, B. Yang, V. Kielstein, S. Dunlop, W. Halangk, A.G. Demaine, A.N. Kingsnorth (Germany)
    [Abstract (PDF)]


  4. A Rapid PCR-RFLP Assay for the Detection of the N34S Mutation in the SPINK1 Gene in Patients with Chronic Pancreatitis
    H. Plendl, R. Siebert, D. Steinemann, W. Grote (Germany)
    [Abstract (PDF)]


  5. Pancreatic Stellate Cells Undergo Apoptosis in Response to Nerve Growth Factor
    F.W. Shek, A.B. Oyetade, F.M.J. Walker, C.D. Johnson, J.P. Iredale, D.R. Fine (UK)
    [Abstract (PDF)]


  6. NK-1 Receptor Expression is Associated with the Pain Syndrome in Chronic Pancreatitits
    H. Friess, SV. Shrikhande, F.F. di Mola, A. Tempia-Caliera, J.R. Conejo Garcia, A. Zimmermann, M.W. Büchler (Switzerland)
    [Abstract (PDF)]


  7. Do Mast Cells Participate in the Induction of Pancreas Fibrosis by Alcohol?
    E. Siegmund, L. Jonas, M. Kasper, P. Schuff-Werner (Germany)
    [Abstract (PDF)]


  8. Autocrine Up-Regulation of CTGF by TGF-1 in Pancreatic Stellate Cell Cultures: Implications for Progressive Fibrosis in Chronic Pancreatitis
    F.W. Shek, E.J. Williams, X. Zhou, F.M.J. Walker, C.D. Johnson, R.C. Benyon, J.P. Iredale, D.R. Fine (UK)
    [Abstract (PDF)]


  9. Neural Alterations are Similar in Alcoholic and Non-alocholic Chronic Pancreatitis
    H. Friess, M.E. Martignoni, S. Shrikhande, M. Shrikhande, A. Zimmermann, A. Kappeler, H. Ramesh, M.W. Büchler (Switzerland, India)
    [Abstract (PDF)]


  10. In Vitro Secretion of Interleukin-18 from Human Peripheral Mononuclear Cells (PBMC) in Chronic Pancreatitis – First Results
    A. Schneider, P. Feick, S. Hass, S. Teyssen, S. Rossol, M.V. Singer (Germany)
    [Abstract (PDF)]



     P7  Chronic Pancreatitis. Clinical Aspects
Top

  1. Clinical and Genetic Characteristics of Patients with Hereditary Pancreatitis (HP) in Europe
    N. Howes, W. Greenhalf, M.M. Lerch, R. Ammann, G. Cavallini, R. Charnley, G. Uomo, M. Delhaye, J. Spicak, J. Jansen, B. Drumm, P. Simon, A. Poll, R. Mountford, I. Ellis, D.C. Whitcomb, J.P. Neoptolemos (UK, Switzerland, Italy, Belgium, Czech Republic, Netherlands, USA)
    [Abstract (PDF)]


  2. Pancreatic Exocrine Function in Preterms Measured by Faecal Elastase 1
    M. Ventrucci, V. Paoletti, L. Corvaglia, M.G. Capretti, M. Middonno, C. Racchini, A. Cipolla, P. Simoni, K. Afandi, G. Faldella, G.P. Salvioli (Italy)
    [Abstract (PDF)]


  3. Is Fecal Pancreatic Elastase-1 Useful in Assessing Pancreatic Function in Preterm Newborn?
    T. Salerno, V. Lucidi, S. Bella, F. Libera, M. Orzalesi, G. Salvatori, G. Seganti, F. Colistro, M. Azzolina, M. Castro (Italy)
    [Abstract (PDF)]


  4. Optimization of 13C-Mixed-Triglyceride Breath Test (13C-MTG) for Diagnosis of Steatorrhea: Which Test Meal?
    J. Iglesias-García, M. Vilariño, M.V. Lourido, Tejada, M. Arenas, J.E. Dominguez-Muñoz (Spain)
    [Abstract (PDF)]


  5. Development and Evaluation of a New ELISA for the Quantification of Classical Pancreatic Lipase in Human Sera
    P. Grandval, A. DeCaro, R. Laugier (France)
    [Abstract (PDF)]


  6. Immune Dysfunction in Chronic Pancreatitis?
    W. Schlosser, F. Gansauge, S. Schlosser, S. Gansauge, H.G. Berger (Germany)
    [Abstract (PDF)]


  7. Inhibition of Endogenous Pancreatic Enzyme Secretion by Oral Enzyme Treatment
    J. Walkowiak, K. Strzykala, B. Bychowiec, T. Songi, K. Greberski, K.H. Herzig (Poland, Germany)
    [Abstract (PDF)]


  8. Inhibition of Gastrointestinal Lipolysis by Orlistat during Digestion of Test Meals in Healthy Volunteers
    F. Carrière, C. Renou, S. Ransac, V. Lopez, J. De Caro, F. Ferrato, A. De Caro, A. Fleury, P. Sandwald-Ducray, H. Lengsfeld, C. Beglinger, P. Hadvary, R. Verger, R. Laugier. (Switzerland)
    [Abstract (PDF)]


  9. Cystic Distrophy of the Duodenal Wall (CDDW): The Verona Experience
    L. Frulloni, R. Turrini, P. Bovo, B. Vaona, B. Calore, C. Liani, A. Cantone, M. Falconi, G. Zamboni, G. Bogina, C. Biasutti, G. Cavallini (Italy)
    [Abstract (PDF)]


  10. Report of a Trial of a Leukotriene Receptor Antagonist in Chronic Pancreatitis in Humans
    M.T. Cartmell, D.A. O’Reilly, C. Porter, D. Wright, M. Marner, A.N. Kingsnorth (UK)
    [Abstract (PDF)]


  11. The Long Term Efficacy of Endoscopy Treatment in Chronic Pancreatitis
    J.M. Baudin, L. Heyries, M. Barthet, J.P. Bernard, J. Sahel (France)
    [Abstract (PDF)]


  12. Quality of Life & Nutritional Status after Surgery for Chronic Pancreatitis: A Longitudinal Follow-Up Study
    B. Tihanyi, Zs. Csapó, I. Farkas, K. Bor, R. Schwab, A. Pap, T. Tihanyi (Hungary)
    [Abstract (PDF)]


  13. Quality of Life and Outcomes After Surgical Treatment of Chronic Pancreatitis
    J. Martin, T. Ratia, A. Gutiérrez, J. Mugüerza, A. López, I. Lasa, P. Hernández, J. Granell (Spain)
    [Abstract (PDF)]


  14. Long Term Follow-up of Early Chronic Pancreatitis Diagnosed at Endoscopic Ultrasonography
    L. Heyries, M. Barthet, L. Buscail, P. Pages, J. Escourrou, J. Sahel (France)
    [Abstract (PDF)]


  15. Epidemiology of Pancreatic Diseases in a Defined German Population
    P.G. Lankisch, C. Assmus, P. Maisonneuve, A.B. Lowenfels (Italy, USA)
    [Abstract (PDF)]


  16. Incidence, Mortality Rate and Misdiagnosis of Chronic Pancreatitis in Latvia
    A. Pukitis, J. Pokrotnieks, A. Danilans (Latvia)
    [Abstract (PDF)]


  17. Open-Label Oral Pancreatic Enzyme Therapy for the Treatment of Steatorrhea in HIV-Infected Patients
    A. Carrocio, A. Guarino, G. Zuin, F. Verghi, R. Berni Canani, M. Fontana, N. Fasano, G. Montalto (Italy)
    [Abstract (PDF)]



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