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Announcement
		North American Pancreatic Study Group joins Pancreatology's Triple Membership Program! PancreasWeb 21/01/09 This program (initiated in 2003) allows pancreatologists to become a member of the North American Pancreatic Study Group (NAPSG), the International Association of Pancreatology (IAP) and the European Pancreatic Club (EPC) for the very attractive flat fee of USD 200.00. In addition, triple members receive an online subscription to the journal Pancreatology and can profit from reduced registration fees for IAP and EPC meetings. Application form

News
		PancreasWeb 21/07/09 Scientists at the University of Liverpool, UK, have identified a gene that seems to be involved in alcohol-related pancreatitis. Combining with fatty acids in the pancreas, alcohol can trigger an excessive release of stored calcium ions, which in turn activate intercellular trypsin and lead to acinar cell necrosis. Professor Petersen and his team, in collaboration with the RIKEN Brain Science Institute in Japan, have now identified channels within special …
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		PancreasWeb 31.03.2009 According to researchers from the M.D. Anderson Cancer Center in Houston, TX, obesity greatly increases the risk for metastasis, recurrence and death in pancreatic cancer patients. The study, conducted by Jason B. Fleming, MD, and his team, included 285 patients who underwent potentially curative surgery for pancreatic adenocarcinoma. Overall median time
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		PancreasWeb 30.01.2009 According to researchers from the MD Anderson Cancer Center, University of Texas, variations in mismatch repair genes can help predict treatment response and prognosis in patients with pancreatic cancer. ‘There has been no biomarker for pancreatic cancer used in the clinic to predict response. Our research interest has been to determine whether genetic variation in DNA repair …
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		PancreasWeb 22/08/08 Following up on the hypothesis that pancreatic neoplasia may be initiated in progenitor-like cells, researchers from the Johns Hopkins University School of Medicine in Baltimore, Md., have created a zebrafish model of pancreatic cancer.
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		PancreasWeb 18/06/08 Results of a new study suggest that patients suffering from pancreatic cancer may benefit from a new treatment strategy involving gemcitabine. Richard Schilsky, MD, from the University of Chicago recently presented the results of a trial on the effects of gemcitabine administered after pancreatic cancer surgery. The researchers found that treatment with gemcitabine, compared to placebo, resulted in improvements in both disease-free and overall survival: …
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		PancreasWeb 28/04/08 Resveratrol, a natural antioxidant found in grape skins and wine, is believed to have anti-cancer, anti-inflammatory and anti-atherogenic effects, and to modulate cell growth. Researchers from the University of Rochester Medical Center (New York) have now shown that this agent can also help destroy pancreatic cancer cells by impairing mitochondria function. …
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		PancreasWeb 24/04/08 This book, Vol. 12 of the series 'Endocrine Development', presents in vivo and in vitro techniques to investigate pancreas development and islet cell function, as well as some reviews dealing with genetics. Special emphasis is placed on the investigation, management and treatment of neonatal diabetes. For further information about this title, visit its homepage
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		PancreasWeb 03/03/08 Until now, the existence of pancreatic stem cells in adult organisms has been questioned due to the lack of evidence to support this hypothesis. Previous studies suggested that the replication of adult β cells may be responsible for new β cells, rather than stem cells. Harry Heimberg, MD, and his team from the Juvenile Diabetes Research Foundation Center at Vrije Universiteit Brussel, Belgium, have now succeeded in isolating pancreatic β cell progenitors in adult mice: …

Commentary
		Alcohol use and cigarette smoking as risk factors for post-endoscopic retrograde cholangiopancreatography pancreatitis Debenedet, A.T., Raghunathan, T.E., Wing, J.J., Wamsteker, E.J., Dimagno, M.J. Clinical Gastroenterology and Hepatology 2009;7:353-358 PancreasWeb 29/04/09 Acute pancreatitis is the most common complication of ERCP, with a reported frequency of post-ERCP pancreatitis (PEP) ranging from 5 to 32% (1). PEP is defined as onset of new abdominal pain usually within 2h of completion of the procedure, persisting for a duration of at least 24h, and associated with a 3-fold elevation in serum amylase and/or lipase 24h after the procedure. In the majority of patients, PEP is mild, requiring only conservative treatment. The risk of PEP is determined …
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		Overexpression of Interleukin-1β in the Murine Pancreas Results in Chronic Pancreatitis Frederic Marrache et al. Gastroenterology 2008;135:1277-1287 PancreasWeb 08/11/08
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		Aggressive pancreatic resection for primary pancreatic neuroendocrine tumor: is it justifiable? Swee H. Teh, Clifford Deveney, Brett C. Sheppard Am J Surg 2007;193:610-613 PancreasWeb 14/05/07
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		Potential of adipocytokines in predicting peripancreatic necrosis and severity in acute pancreatitis: Pilot study Andreas Schäffler, Karin Landfried, Markus Völk, Alois Fürst, Christa Büchler, Jürgen Schölmerich, Hans Herfath J Gastroenterol Hepatol 2007;22:326-334 PancreasWeb 26/04/07
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		Early Endoscopic Intervention Versus Early Conservative Management in Patients with Acute Gallstone Pancreatitis and Biliopancreatic Obstruction. A Randomized Clinical Trial Oria A., Cimmino D., Ocamp C., Silva W., Kohan G., Zandalazini H., Szelagowski C., Chiappetta L. Ann Surg 2007;245:10-17 PancreasWeb 29/03/07

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